The Cardiovascular Benefits of NMN: Enhancing Heart Health in Athletes

Nicotinamide Mononucleotide (NMN) is not just a supplement for aging and general health; it’s becoming a key component in the athletic world for its potential cardiovascular benefits. Athletes, who demand high performance from their hearts, can particularly benefit from NMN’s ability to restore heart and blood vessel function. This article examines recent human trials on NMN, shedding light on its role in preventing heart damage and failure, aspects crucial for athletic endurance and performance.

Restoration of Cardiac Mitochondrial Homeostasis for Athletes

A study by Zhang R, Shen Y, Zhou L, et al., in the Journal of Cardiovascular Pharmacology and Therapeutics, demonstrates NMN’s role in preserving cardiac mitochondrial health​​. For athletes, this is crucial as mitochondrial health directly impacts muscle performance and energy levels. The study’s findings suggest that NMN supplementation can support the heart’s mitochondria, essential for athletes who constantly push their cardiovascular limits.

The Cardiovascular Benefits of NMN

NMN’s Protective Role Against Heart Failure in High-Performance Scenarios

Athletes, especially those in endurance and high-intensity sports, often push their cardiovascular systems to the extreme. The study’s revelation that short-term NMN administration can prevent heart failure is particularly relevant. By maintaining heart health and function, NMN can be a vital supplement for athletes, aiding in their overall cardiovascular resilience and performance.

Implications for Athletes

The cardiovascular benefits of NMN could mean a significant advancement in sports health and athlete longevity. With heart disease being a concern even among athletes, NMN’s potential to bolster heart health is a promising prospect. This could translate into better performance, reduced risk of heart-related health issues, and an overall enhancement in athletic longevity.

Athlete-Specific Insights

Athletes considering NMN

supplementation should view it as a part of a broader health strategy. While NMN shows promise in supporting cardiovascular health, it is essential for athletes to consult with healthcare professionals to determine the appropriate dosage and integration into their training regimen. The potential of NMN to improve heart efficiency, endurance, and recovery after intense workouts could make it a valuable addition to an athlete’s nutritional arsenal.


For athletes, maintaining cardiovascular health is not just about peak performance—it’s also about longevity in their sports careers. The emerging research on NMN, particularly studies like that of Zhang R, Shen Y, Zhou L, et al., presents a compelling case for its use in supporting heart health. As more research unfolds, NMN could become a staple in sports nutrition, offering a new dimension of cardiovascular care for athletes.


  • Zhang R, Shen Y, Zhou L, et al. (2020). “Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure.” Journal of Cardiovascular Pharmacology and Therapeutics, 25(3), 240-250. doi: 10.1177/1074248419882002.